From the railway station "Frankfurt Airport" trains go to Nürnberg
Hauptbahnhof (main railway station). In Nürnberg you have to change
trains to Bayreuth. Total travel time is about 4 hours.
The Underground (U-Bahn) takes you from the airport to the main
railway station. There you take the trains to Bayreuth. Total travel time
is about 1.5 hours.
Take the train from München to Nürnberg where you have
to change for the train to Bayreuth. Total travel time is about 4 hours.
By train
In most cases, you travel by train via Nürnberg Hauptbahnhof
(main railway station). The express train from Nürnberg to Bayreuth
goes every hour between early morning and late evening. A few times per day
you can take an ICE.